Science and Development of Muscle Hypertrophy, Second Edition, is the most comprehensive resource on muscle hypertrophy in the world. Written by Brad Schoenfeld, PhD, an internationally renowned expert on muscle hypertrophy, this book is the definitive resource for strength and conditioning professionals, personal trainers, sport scientists, researchers, and exercise science instructors who are seeking information regarding muscle hypertrophy, including the mechanism of its development, how the body structurally and hormonally changes when exposed to stress, ways to most effectively design training programs, and nutritional guidelines for eliciting hypertrophic changes.
This new edition offers more than 1,000 references and applied guidelines. Two all-new chapters deliver practical content on the measurement of muscle hypertrophy and advanced training practices. Readers will learn various methods by which hypertrophy is measured, including site-specific measures (circumference measures, MRI, CT, and ultrasound), indirect measures (underwater weighing, DXA, BIA, ADP, and skinfolds), and histological measures (biopsy), as well as the strengths and limitations of each modality. The new edition also provides guidance for achieving greater training volumes with training practices that maximize the individual’s genetic potential to gain muscle.
No other resource offers a comparable amount of content solely focused on the science of muscle hypertrophy and its application to designing training programs. The full-color book offers several features to make the content accessible to readers:
- Research Findings sidebars highlight the aspects of muscle hypertrophy currently being examined to encourage readers to re-evaluate their knowledge and ensure their training practices are up to date.
- Practical Applications sidebars outline how to apply the research conclusions for maximal hypertrophic development.
- Comprehensive subject and author indexes optimize the book’s use as a reference tool.
Although muscle hypertrophy can be attained through a range of training programs, this book allows readers to understand and apply the specific responses and mechanisms that promote optimal muscle hypertrophy. It explores how genetic background, age, sex, and other factors have been shown to mediate the hypertrophic response to exercise, affecting both the rate and the total gain in lean muscle mass. Sample programs show how to design a three- or four-day-per-week undulating periodized program and a modified linear periodized program for maximizing muscular development.
Science and Development of Muscle Hypertrophy is an invaluable resource for those seeking to maximize hypertrophic gains for themselves or their athletes or clients and for those searching for the most comprehensive and authoritative research in the field.













edwin (verified owner) –
Folks, if you’re looking to maximize your knowledge about how to take your gains to the next level from a scientific standpoint, this is your best bet!!!!
Varoon Seepersad (verified owner) –
10/10 recommend for serious athletes and those who will appreciate the deep science behind all aspects of it. Backed by evidence and a goldmine.
Niels Wildschut (verified owner) –
The book is a most have in my opinion if you want to be up to date on the most valuable information regarding muscle hypertrophy. A solid knowledge base is needed before starting the book, which is obvious. It brought my ‘expertise’ to a whole new level. Would recommend it to everyone interested in bodybuilding/muscle hypertrophy.
David Iglesias (verified owner) –
Brad’s one of the leading researchers in the world in regards to muscle hypertrophy, so I knew this book would be packed with info that’s up to date. He doesn’t let down and I highly recommend his book.
Tom Reifsnyder (verified owner) –
The amount of work put into this book is unbelievable, but it’s no surprise, as it’s written by the world’s leader in muscle hypertrophy research. That being said, Dr. Schoenfeld is able to carefully explain each complex process and detail related to the muscle building phenomenon without missing a detail, while still writing in a manner entertaining and mild enough for many casual readers to at least grasp the main points of what he’s aiming to get across. This is no ordinary “textbook.” It’s truly a masterclass in artfully detailing the full history and most recent findings in the field of muscle hypertrophy research.
ryan wooley (verified owner) –
There is no other textbook out there that dives into the science and evidence of muscle hypertrophy like this one does.
Be warned though, this book goes heavy into the research. It is not just a book of training programs andyer exercises. But if you want to understand the why behind hypertrophy training, this book is unparallelled.
Zackary Meaders (verified owner) –
This book is excellent and concise. It has just enough information about the biological mechanisms that cause muscle growth but not too much to put the average person to sleep. It offers everything you’ll need to know to develop your own muscle growth strategies in one book. Plus, it’s all supported with references if you want to to do further research. This book is amazing.
Craig (verified owner) –
This book is excellent! It covers a lot of up to date information like hypertrophy mechanisms, training variables, programming, and nutrition. An excellent resource!
Christopher Lewis (verified owner) –
By far one of the best books I have purchased in a long time. A must have for all in the fitness industry
P (verified owner) –
Best book on how to build muscle!
Jake Shute (verified owner) –
The best book from a scientific view on hypertrophy. If you are serious about growing muscle this book along with max muscle plan and mike Izratel are the best resources
Carlysle Bourne (verified owner) –
I was lucky to buy the last one.
Qigong (verified owner) –
Understanding how the body builds muscle
mass increases knowledge and purpose in
motivation for exercise.